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PRKAG3 抗体 (AA 1-210)

PRKAG3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7142683
发货至: 中国
  • 抗原 See all PRKAG3 抗体
    PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
    抗原表位
    • 15
    • 8
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    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
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    AA 1-210
    适用
    • 57
    • 12
    • 1
    宿主
    • 49
    • 9
    • 1
    克隆类型
    • 50
    • 9
    多克隆
    标记
    • 23
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    • 3
    • 3
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    • 2
    • 2
    • 2
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    • 1
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    This PRKAG3 antibody is un-conjugated
    应用范围
    • 50
    • 27
    • 13
    • 13
    • 10
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
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    Western Blotting (WB), ELISA
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human 5\\\'-AMP-activated protein kinase subunit gamma-3 protein (1-210AA)
    亚型
    IgG
    Top Product
    Discover our top product PRKAG3 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:2000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
    别名
    PRKAG3 (PRKAG3 产品)
    别名
    Ampkg3 antibody, prkag3-a antibody, PRKAG3 antibody, AMPKG3 antibody, AMPKg3L antibody, AMPKg3S antibody, Amkg3 antibody, protein kinase AMP-activated non-catalytic subunit gamma 3 antibody, protein kinase, AMP-activated, gamma 3 non-catalytic subunit S homeolog antibody, protein kinase, AMP-activated, gamma 3 non-catatlytic subunit b antibody, protein kinase, AMP-activated, gamma 3 non-catatlytic subunit antibody, Prkag3 antibody, PRKAG3 antibody, prkag3.S antibody, prkag3-b antibody
    背景

    Background: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.

    Aliases: 5 AMP activated protein kinase subunit gamma 3 antibody, 5''-AMP-activated protein kinase subunit gamma-3 antibody, AAKG3_HUMAN antibody, AMPK gamma 3 chain antibody, AMPK gamma3 antibody, AMPK subunit gamma-3 antibody, AMPKG3 antibody, PRKAG3 antibody, Protein kinase AMP activated gamma 3 non catalytic subunit antibody

    UniProt
    Q9UGI9
    途径
    AMPK Signaling, Cellular Glucan Metabolic Process, Warburg Effect
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