LexA (AA 1-202) 抗体 (HRP)
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- 抗原
- LexA
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抗原表位
- AA 1-202
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适用
- E. coli
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- HRP
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应用范围
- ELISA
- 交叉反应
- E. coli
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Escherichia coli LexA repressor protein (1-202AA)
- 亚型
- IgG
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anti-LexA (AA 1-202) antibody
适用: E. coli ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-LexA (DNA Binding Domain) antibody适用: 化学剂 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- LexA
- 背景
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Background: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5\'-CTGTATATATATACAG-3\'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. Implicated in hydroxy radical-mediated cell death induced by hydroxyurea treatment (PubMed:20005847).The SOS response controls an apoptotic-like death (ALD) induced (in the absence of the mazE-mazF toxin-antitoxin module) in response to DNA damaging agents that is mediated by RecA and LexA (PubMed:22412352).
Aliases: lexA antibody, exrA antibody, spr antibody, tsl antibody, umuA antibody, b4043 antibody, JW4003LexA repressor antibody, EC 3.4.21.88 antibody
- UniProt
- P0A7C2
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