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CD14 抗体

This anti-CD14 antibody is a 小鼠 单克隆 antibody detecting CD14 in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7140933
发货至: 中国

Quick Overview for CD14 抗体 (ABIN7140933)

抗原

See all CD14 抗体
CD14

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD14 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA

克隆位点

1A3B6
  • 交叉反应

    纯化方法

    Protein G purified

    免疫原

    Recombinant CD14 Protein

    亚型

    IgG2b
  • 应用备注

    Recommended dilution:IHC:1:50-1:500,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CD14

    别名

    CD14

    背景

    Background: As a component of the innate immune system, the cell surface glycoprotein CD14 is a myelomonocytic differentiation antigen preferentially expressed on monocytes, macrophages, and activated granulocytes. CD14 exists as two forms, either anchored into the membrane by a GPI-anchor tail (mCD14) or present as a soluble form (sCD14) in normal serum and body fluids. CD14 was first described as a pattern recognition receptor for lipopolysaccharide (LPS) and a variety of ligands derived from different microbial sources, along with the co-receptors Toll-like receptor TLR 4 and MD-2. The binding of CD14 and LPS depends on the presence and catalytic activity of lipopolysaccharide-binding protein (LBP). Besides its endotoxin signaling function, CD14 has been proposed to be involved in various biological processes, including transportation of other lipids, cell-cell interaction during different immune responses, as well as recognition of apoptotic cells. Multiple transcript variants resulting from alternative splicing encode the same isoform of CD14.

    Aliases: CD14, CD14 Molecule

    UniProt

    P08571

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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