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RABAC1 抗体 (AA 16-299)

RABAC1 适用: Candida albicans ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7380344
发货至: 中国
  • 抗原 See all RABAC1 抗体
    RABAC1 (Rab Acceptor 1 (Prenylated) (RABAC1))
    抗原表位
    • 4
    • 1
    • 1
    • 1
    AA 16-299
    适用
    • 5
    • 4
    • 1
    • 1
    Candida albicans
    宿主
    • 8
    • 1
    克隆类型
    • 8
    • 1
    多克隆
    标记
    • 6
    • 1
    • 1
    • 1
    This RABAC1 antibody is un-conjugated
    应用范围
    • 7
    • 6
    • 2
    ELISA, Western Blotting (WB)
    交叉反应
    Candida albicans
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Candida albicans pH-regulated antigen PRA1 protein (16-299AA)
    亚型
    IgG
    Top Product
    Discover our top product RABAC1 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    RABAC1 (Rab Acceptor 1 (Prenylated) (RABAC1))
    别名
    PRA1 (RABAC1 产品)
    别名
    PRA1 antibody, PRAF1 antibody, YIP3 antibody, 2310040I06Rik antibody, Gbpap1 antibody, prenylin antibody, Pra1 antibody, wu:fe26d12 antibody, zgc:86749 antibody, MGC81207 antibody, pra1 antibody, yip3 antibody, praf1 antibody, MGC146421 antibody, F22K20.5 antibody, F22K20_5 antibody, Rab acceptor 1 antibody, Rab acceptor 1 (prenylated) antibody, Rab acceptor 1 (prenylated) S homeolog antibody, Rab acceptor 1 (prenylated) L homeolog antibody, Regulator of chromosome condensation (RCC1) family with FYVE zinc finger domain-containing protein antibody, RABAC1 antibody, Rabac1 antibody, rabac1 antibody, rabac1.S antibody, rabac1.L antibody, PRAF1 antibody
    背景

    Background: Cell surface protein involved in the host-parasite interaction during candidal infection. With MP65, represents a major component of the biofilm matrix. Sequesters zinc from host tissue and mediates leukocyte adhesion and migration. As a surface protein, binds the two human complement regulators CFH and CFHR1, as well as plasminogen PLG, mediates complement evasion and extra-cellular matrix interaction and/or degradation. As a released protein, enhances complement control in direct vicinity of the yeast and thus generates an additional protective layer which controls host complement attack, assisting the fungus in escaping host surveillance. Binds to host fluid-phase C3 and blocks cleavage of C3 to C3a and C3b, leading to inhibition of complement activation. Mediates also human complement control and complement evasion through binding to C4BPA, another human complement inhibitor, as well as through binding to host integrin alpha-M/beta-2. Decreases complement-mediated adhesion, as well as uptake of C.albicans by human macrophages.

    Aliases: PRA1 antibody, FBP1 antibody, CAALFM_C406980WA antibody, CaO19.10623 antibody, CaO19.3111 antibody, pH -regulated antigen PRA1 antibody, 58 kDa fibrinogen-binding mannoprotein antibody

    UniProt
    P87020
    途径
    Chromatin Binding
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