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RPA1 抗体

This anti-RPA1 antibody is a 小鼠 单克隆 antibody detecting RPA1 in WB, ELISA, ICC 和 IP. Suitable for 人.
产品编号 ABIN7140348
发货至: 中国
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Quick Overview for RPA1 抗体 (ABIN7140348)

抗原

See all RPA1 抗体
RPA1 (Replication Protein A1, 70kDa (RPA1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This RPA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunoprecipitation (IP)
  • 原理

    RPA1 Monoclonal Antibody

    交叉反应

    猴, 小鼠, 大鼠

    纯化方法

    Affinity purified

    免疫原

    Purified recombinant human RPA70 protein fragments expressed in E.coli.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified mouse monoclonal antibody in PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    RPA1 (Replication Protein A1, 70kDa (RPA1))

    别名

    RPA1

    背景

    Background: Plays an essential role in several cellular processes in DNA metabolism including replication,recombination and DNA repair.Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing.Functions as component of the alternative replication protein A complex (aRPA).aRPA binds single-stranded DNA and probably plays a role in DNA repair,it does not support chromosomal DNA replication and cell cycle progression through S-phase.In vitro,aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC),the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.

    Aliases: Dmrpa1, Drosophila Replication Protein A, DRPA, HSSB, Human single stranded DNA binding protein, MST075, MSTP075, p70, REPA1, Replication factor A, Replication factor A protein 1, Replication protein A 70 kDa DNA-binding subunit,

    UniProt

    P27694

    途径

    Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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