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- 抗原 See all CENPA 抗体
- CENPA (Centromere Protein A (CENPA))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CENPA antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Peptide sequence around site of Ser (7) derived from Human Histone H3-like centromeric protein A
- 亚型
- IgG
- Top Product
- Discover our top product CENPA Primary Antibody
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anti-Centromere Protein A (CENPA) (pSer16), (pSer18) antibody
CENPA 适用: 人 WB, IF, ICC, DB 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein A (CENPA) (AA 65-140) antibodyCENPA 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein A (CENPA) (AA 1-100) antibodyCENPA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein A (CENPA) antibodyCENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 unconjugated
anti-Centromere Protein A (CENPA) antibody (HRP)CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 HRP
anti-Centromere Protein A (CENPA) antibody (FITC)CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 FITC
anti-Centromere Protein A (CENPA) antibody (Biotin)CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 Biotin
anti-Centromere Protein A (CENPA) antibody (PE)CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 PE
anti-Centromere Protein A (CENPA) antibody (APC)CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 APC
anti-Centromere Protein A (CENPA) antibody (PerCP)CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 PerCP
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- 应用备注
- Recommended dilution: IHC:1:10-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CENPA (Centromere Protein A (CENPA))
- 别名
- CENPA (CENPA 产品)
- 别名
- CENP-A antibody, CenH3 antibody, Cenp-A antibody, cenpx antibody, cenp-a antibody, sim2 antibody, Cenp-a antibody, RGD1563607 antibody, CENPA antibody, centromere protein A antibody, centromere protein-A antibody, centromeric histone-3 like protein antibody, centromere-specific histone H3 CENP-A antibody, cenp-A antibody, centromere protein A L homeolog antibody, histone H3-like centromeric protein A antibody, CENPA antibody, Cenpa antibody, CENP-A antibody, cenpa antibody, cenp-A antibody, cnp1 antibody, HAN_3g422 antibody, Cenp-a antibody, cenpa.L antibody, CMU_016480 antibody
- 背景
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Background: Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes (PubMed:7962047, PubMed:9024683, PubMed:11756469, PubMed:14667408, PubMed:15702419, PubMed:15475964, PubMed:15282608, PubMed:17651496, PubMed:19114591, PubMed:27499292, PubMed:20739937). Replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore (PubMed:18072184). The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3 (PubMed:27499292, PubMed:26878239). May serve as an epigenetic mark that propagates centromere identity through replication and cell division (PubMed:15475964, PubMed:15282608, PubMed:26878239, PubMed:20739937, PubMed:21478274). Required for recruitment and assembly of kinetochore proteins, and as a consequence required for progress through mitosis, chromosome segregation and cytokinesis (PubMed:11756469, PubMed:14667408, PubMed:18072184, PubMed:23818633, PubMed:25556658, PubMed:27499292).
Aliases: CENP A antibody, CENP-A antibody, cenpa antibody, CENPA_HUMAN antibody, Centromere autoantigen A antibody, Centromere protein A 17 kDa antibody, Centromere protein A antibody, Histone H3 like centromeric protein A antibody, Histone H3-like centromeric protein A antibody
- UniProt
- P49450
- 途径
- Chromatin Binding, Maintenance of Protein Location
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