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EPOR 抗体 (pTyr368)

EPOR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138993
发货至: 中国
  • 抗原 See all EPOR 抗体
    EPOR (Erythropoietin Receptor (EPOR))
    抗原表位
    • 16
    • 11
    • 10
    • 8
    • 7
    • 7
    • 6
    • 5
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    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    pTyr368
    适用
    • 119
    • 59
    • 49
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 106
    • 17
    • 5
    • 1
    克隆类型
    • 114
    • 15
    多克隆
    标记
    • 63
    • 15
    • 7
    • 5
    • 5
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    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
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    This EPOR antibody is un-conjugated
    应用范围
    • 89
    • 45
    • 24
    • 23
    • 22
    • 15
    • 14
    • 14
    • 11
    • 5
    • 5
    • 5
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    • 1
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    Western Blotting (WB), ELISA
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of Tyrosine 368 (D-T-Y(p)-L-V) derived from Human Epo-R.
    亚型
    IgG
    Top Product
    Discover our top product EPOR Primary Antibody
  • 应用备注
    WB:1:500-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    EPOR (Erythropoietin Receptor (EPOR))
    别名
    EPOR (EPOR 产品)
    别名
    EPOR antibody, epor antibody, EPO-R antibody, erythropoietin receptor antibody, erythropoietin receptor L homeolog antibody, EPOR antibody, epor antibody, Epor antibody, epor.L antibody
    背景

    Background:

    Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.

    Funakoshi-Tago M, et al. (2010) J Biol Chem 285, 5296-307
    Sulahian R, Cleaver O, Huang LJ (2009) Blood 113, 5287-97
    Zhang YL, et al. (2009) Mol Cell 33, 266-74

    Aliases: EPO R antibody, EPO Receptor antibody, EPO-R antibody, epor antibody, EPOR_HUMAN antibody, Erythropoietin receptor antibody, Erythropoietin receptor precursor antibody, MGC138358 antibody

    UniProt
    P19235
    途径
    JAK/STAT Signaling
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