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IGF1R 抗体 (pTyr1165, pTyr1166)

IGF1R 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138914
发货至: 中国
  • 抗原 See all IGF1R 抗体
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    抗原表位
    • 22
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    pTyr1165, pTyr1166
    适用
    • 187
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    宿主
    • 172
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    克隆类型
    • 174
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    多克隆
    标记
    • 126
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    This IGF1R antibody is un-conjugated
    应用范围
    • 131
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    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of tyrosine 1165/tyrosine 1166 (T-D-Y(p)-Y(p)-R-K) derived from Human IGF-1R .
    亚型
    IgG
    Top Product
    Discover our top product IGF1R Primary Antibody
  • 应用备注
    WB:1:500-1:1000, IF:1:100-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    别名
    IGF1R (IGF1R 产品)
    背景

    Background: This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.

    Li S, et al. (1994) J Biol Chem, 269(51): 32558-64.

    Aliases: CD221 antibody, CD221 antigen antibody, IGF 1 receptor antibody, IGF 1R antibody, IGF I receptor antibody, IGF-I receptor antibody, Igf1r antibody, IGF1R_HUMAN antibody, IGFIR antibody, IGFIRC antibody, IGFR antibody, Insulin like growth factor 1 receptor antibody, Insulin like growth factor 1 receptor precursor antibody, Insulin-like growth factor 1 receptor beta chain antibody, Insulin-like growth factor I receptor antibody, JTK13 antibody, MGC142170 antibody, MGC142172 antibody, MGC18216 antibody, Soluble IGF1R variant 1 antibody, Soluble IGF1R variant 2 antibody

    UniProt
    P08069
    途径
    RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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