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IGF1R 抗体 (pTyr1165, pTyr1166)

This anti-IGF1R antibody is a 兔 多克隆 antibody detecting IGF1R in WB, ELISA 和 IF. Suitable for 人.
产品编号 ABIN7138914
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IGF1R 抗体 (pTyr1165, pTyr1166) (ABIN7138914)

抗原

See all IGF1R 抗体
IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

适用

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宿主

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克隆类型

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多克隆

标记

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This IGF1R antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
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    pTyr1165, pTyr1166

    原理

    Phospho-IGF1R (Tyr1165/Tyr1166) Antibody

    交叉反应

    小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of tyrosine 1165/tyrosine 1166 (T-D-Y(p)-Y(p)-R-K) derived from Human IGF-1R .

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

    别名

    IGF1R

    背景

    Background: This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.

    Li S, et al. (1994) J Biol Chem, 269(51): 32558-64.

    Aliases: CD221 antibody, CD221 antigen antibody, IGF 1 receptor antibody, IGF 1R antibody, IGF I receptor antibody, IGF-I receptor antibody, Igf1r antibody, IGF1R_HUMAN antibody, IGFIR antibody, IGFIRC antibody, IGFR antibody, Insulin like growth factor 1 receptor antibody, Insulin like growth factor 1 receptor precursor antibody, Insulin-like growth factor 1 receptor beta chain antibody, Insulin-like growth factor I receptor antibody, JTK13 antibody, MGC142170 antibody, MGC142172 antibody, MGC18216 antibody, Soluble IGF1R variant 1 antibody, Soluble IGF1R variant 2 antibody

    UniProt

    P08069

    途径

    RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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