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- 抗原 See all CAD 抗体
- CAD (Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))
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抗原表位
- pThr456
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CAD antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- 免疫原
- Peptide sequence around phosphorylation site of threonine 456 (P-I-T(p)-P-H) derived from Human CAD.
- 亚型
- IgG
- Top Product
- Discover our top product CAD Primary Antibody
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anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) antibody
CAD 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (AA 1650-1900) antibodyCAD 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (AA 780-809) antibodyCAD 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18384 unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (AA 780-809) antibodyCAD 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) antibodyCAD 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (C-Term) antibodyCAD 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) antibodyCAD 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (N-Term) antibodyCAD 适用: 人, 小鼠, 大鼠, 犬, 马, 豚鼠, Cow, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (AA 205-222) antibodyCAD 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (AA 2018-2067) antibodyCAD 适用: 人, 小鼠, 大鼠, 犬, 兔, 马, Cow, 斑马鱼, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC:1:50-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CAD (Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))
- 别名
- CAD (CAD 产品)
- 别名
- Cpad antibody, AU018859 antibody, 2410008J01Rik antibody, cb456 antibody, wu:fc30c12 antibody, wu:fc33d01 antibody, wu:fc67g02 antibody, si:dkey-221h15.3 antibody, CAD antibody, xcad antibody, carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase antibody, CAD antibody, Cad antibody, cad antibody
- 背景
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Background:
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
Iwahana H., Biochem. Biophys. Res. Commun. 219:249-255(1996).
Davidson J.N., DNA Cell Biol. 9:667-676(1990).
Olsen J.V., Cell 127:635-648(2006).Aliases: CAD antibody, CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase antibody, EC 6.3.5.5), Aspartate carbamoyltransferase antibody, EC 2.1.3.2), Dihydroorotase antibody, EC 3.5.2.3)] antibody
- UniProt
- P27708
- 途径
- Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process
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