NFKBIB 抗体 (pThr19)
Quick Overview for NFKBIB 抗体 (pThr19) (ABIN7138792)
抗原
See all NFKBIB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr19
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交叉反应
- 人, 小鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of Threonine 19(C-D-S(p)-G-L) derived from Human IkappaB- beta.
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亚型
- IgG
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应用备注
- WB:1:500-1:1000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
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别名
- NFKBIB
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背景
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Background: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
Aliases: I kappa B beta antibody, I-kappa-B-beta antibody, IkappaBbeta antibody, IKB beta antibody, IkB-B antibody, IkB-beta antibody, IKBB antibody, IKBB_HUMAN antibody, IkBbeta antibody, NF kappa BIB antibody, NF-kappa-B inhibitor beta antibody, NF-kappa-BIB antibody, Nfkbib antibody, Thyroid receptor interacting protein 9 antibody, Thyroid receptor-interacting protein 9 antibody, TR interacting protein 9 antibody, TR-interacting protein 9 antibody, TRIP-9 antibody, TRIP9 antibody
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UniProt
- Q15653
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途径
- NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
抗原
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