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AFT1 抗体 (pSer63)

AFT1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138665
发货至: 中国
  • 抗原 See all AFT1 抗体
    AFT1 (Activating Transcription Factor 1 (AFT1))
    抗原表位
    • 27
    • 14
    • 8
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer63
    适用
    • 108
    • 46
    • 25
    • 9
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    宿主
    • 101
    • 7
    • 2
    • 1
    克隆类型
    • 98
    • 13
    多克隆
    标记
    • 58
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AFT1 antibody is un-conjugated
    应用范围
    • 79
    • 36
    • 22
    • 15
    • 15
    • 14
    • 14
    • 10
    • 10
    • 7
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应
    人, 小鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of serine 63(R-P-S(p)-Y-R) derived from Human ATF1 .
    亚型
    IgG
    Top Product
    Discover our top product AFT1 Primary Antibody
  • 应用备注
    WB:1:500-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    AFT1 (Activating Transcription Factor 1 (AFT1))
    别名
    ATF1 (AFT1 产品)
    别名
    ews-atf1 antibody, fus/atf-1 antibody, treb36 antibody, ATF1 antibody, EWS-ATF1 antibody, FUS/ATF-1 antibody, TREB36 antibody, Atf-1 antibody, wu:fc92c07 antibody, zgc:64099 antibody, activating transcription factor 1 antibody, activating transcription factor 1 L homeolog antibody, atf1 antibody, ATF1 antibody, MGC85066 antibody, atf1.L antibody, Atf1 antibody
    背景

    Background:

    This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.

    Mackenzie KF, et al. (2013) J Immunol 190, 565-77
    Dickinson RJ, et al. (2011) J Biol Chem 286, 38018-26
    Wang J, Zhou JY, Wu GS (2011) J Biol Chem 286, 22384-92

    Aliases: Activating transcription factor 1 antibody, ATF 1 antibody, atf1 antibody, ATF1 EWS fusion gene antibody, ATF1 FUS fusion gene antibody, ATF1_HUMAN antibody, cAMP dependent transcription factor 1 antibody, cAMP-dependent transcription factor ATF-1 antibody, Cyclic AMP dependent transcription factor ATF 1 antibody, Cyclic AMP dependent transcription factor ATF1 antibody, Cyclic AMP-dependent transcription factor ATF-1 antibody, EWS AFT1 antibody, FUS ATF 1 antibody, FUS/ATF 1 antibody, Protein TREB36 antibody, RNA binding protein activating transcription factor 1 fusion protein antibody, TREB 36 antibody, TREB36 antibody, TREB36 protein antibody

    UniProt
    P18846
    途径
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades
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