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NFKBIB 抗体 (pSer23)

This anti-NFKBIB antibody is a 兔 多克隆 antibody detecting NFKBIB in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7138495
发货至: 中国

Quick Overview for NFKBIB 抗体 (pSer23) (ABIN7138495)

抗原

See all NFKBIB 抗体
NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

适用

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宿主

  • 99
  • 10

克隆类型

  • 91
  • 18
多克隆

标记

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This NFKBIB antibody is un-conjugated

应用范围

  • 86
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 28
    • 15
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    • 5
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    • 1
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    • 1
    pSer23

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of serine 23 (L-G-S(p)-L-G) derived from Human IkB-b.

    亚型

    IgG
  • 应用备注

    WB:1:500-1:1000, IHC:1:50-1:100,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

    别名

    NFKBIB

    背景

    Background:

    Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

    Shirane, M. et al. (1999) J Biol Chem 274, 28169-28174.
    DiDonato J, et al. (1996) Mol Cell Biol 16(4): 1295-304

    Aliases: I kappa B beta antibody, I-kappa-B-beta antibody, IkappaBbeta antibody, IKB beta antibody, IkB-B antibody, IkB-beta antibody, IKBB antibody, IKBB_HUMAN antibody, IkBbeta antibody, NF kappa BIB antibody, NF-kappa-B inhibitor beta antibody, NF-kappa-BIB antibody, Nfkbib antibody, Thyroid receptor interacting protein 9 antibody, Thyroid receptor-interacting protein 9 antibody, TR interacting protein 9 antibody, TR-interacting protein 9 antibody, TRIP-9 antibody, TRIP9 antibody

    UniProt

    Q15653

    途径

    NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
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