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GRIN2B 抗体 (AA 1250-1254)

GRIN2B 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138056
发货至: 中国
  • 抗原 See all GRIN2B 抗体
    GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
    抗原表位
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    AA 1250-1254
    适用
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    大鼠
    宿主
    • 196
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    克隆类型
    • 198
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    多克隆
    标记
    • 96
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    This GRIN2B antibody is un-conjugated
    应用范围
    • 190
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    Western Blotting (WB), ELISA
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
    免疫原
    Peptide sequence around aa.1250-1254(N-L-Y-D-I) derived from Human NMDANR2B Subunit.
    亚型
    IgG
    Top Product
    Discover our top product GRIN2B Primary Antibody
  • 应用备注
    WB:1:500-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
    别名
    Grin2b (GRIN2B 产品)
    别名
    NMDAR2B antibody, GluN2B antibody, MRD6 antibody, NR2B antibody, hNR3 antibody, nmdar2b antibody, nr2b antibody, AW490526 antibody, Nmdar2b antibody, glutamate ionotropic receptor NMDA type subunit 2B antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2B L homeolog antibody, glutamate receptor, ionotropic, NMDA2B (epsilon 2) antibody, GRIN2B antibody, Grin2b antibody, grin2b.L antibody
    背景

    Background: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death

    Kornau H.C., Schenker L.T., Kennedy M.B., Seeburg P.H.Science 269:1737-1740(1995)
    Kurschner C., Mermelstein P.G., Holden W.T., Surmeier D.J.Mol. Cell. Neurosci. 11:161-172(1998)

    Aliases: Grin2bGlutamate receptor ionotropic antibody, NMDA 2B antibody, GluN2B antibody, Glutamate [NMDA] receptor subunit epsilon-2 antibody, N-methyl D-aspartate receptor subtype 2B antibody, NMDAR2B antibody, NR2B antibody

    UniProt
    Q00960
    途径
    Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
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