SRGAP3 抗体
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- 抗原 See all SRGAP3 抗体
- SRGAP3 (SLIT-ROBO rho GTPase Activating Protein 3 (SRGAP3))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SRGAP3 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antigen affinity purification
- 免疫原
- Fusion protein of Human SRGAP3
- 亚型
- IgG
- Top Product
- Discover our top product SRGAP3 Primary Antibody
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- 应用备注
- ELISA:1:2000-1:5000, IHC:1:25-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SRGAP3 (SLIT-ROBO rho GTPase Activating Protein 3 (SRGAP3))
- 别名
- SRGAP3 (SRGAP3 产品)
- 别名
- AI452337 antibody, Arhgap14 antibody, D130026O08Rik antibody, Gbi antibody, MEGAP antibody, WRP antibody, mKIAA0411 antibody, RGD1563152 antibody, ARHGAP14 antibody, SRGAP2 antibody, RGD1566016 antibody, srGAP2 antibody, fnbp2 antibody, srgap2 antibody, SLIT-ROBO Rho GTPase activating protein 3 antibody, SLIT-ROBO Rho GTPase activating protein 2 antibody, SLIT-ROBO Rho GTPase activating protein 2 L homeolog antibody, Srgap3 antibody, SRGAP3 antibody, Srgap2 antibody, srgap3 antibody, srgap2.L antibody
- 背景
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Background: SRGAP3 is a 1099 amino acid protein containing 1 FCH domain, 1 Rho-GAP domain and 1 SH3 domain. Expressed highly in brain, and in lower levels in kidney, WRP is thought to play a role in cell migration through its interaction with Cdc42 and Rac1. Cdc42 and Rac1 are two intracellular signaling proteins that regulate the multistep cell migration process. WRP downregulates Cdc42 and Rac1 activity, thereby impairing actin and microtubule dynamics, the formation of protrusions, and total cell migration. Defects in the gene encoding WRP have been linked to severe idiopathic mental retardation. Three isoforms of WRP exist as a result of alternative splicing events.
Aliases: ARHGAP 14 antibody, ARHGAP14 antibody, Gbi antibody, ME GAP antibody, MEGAP antibody, Mental disorder associated GAP antibody, Mental disorder-associated GAP antibody, Rho GTPase activating protein 14 antibody, Rho GTPase-activating protein 14 antibody, SLIT ROBO Rho GTPase activating protein 3 antibody, SLIT-ROBO Rho GTPase-activating protein 3 antibody, srGAP 2 antibody, srGAP 3 antibody, srGAP2 antibody, srGAP3 antibody, SRGP 2 antibody, SRGP2 antibody, SRGP3_HUMAN antibody, WAVE associated Rac GTPase activating protein antibody, WAVE-associated Rac GTPase-activating protein antibody, WRP antibody
- UniProt
- O43295
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