Recombinant RHOA 抗体
Quick Overview for Recombinant RHOA 抗体 (ABIN7127793)
抗原
See all RHOA 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human Rho
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亚型
- IgG
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anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-193) antibody
RHOA 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1B12 unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-193) antibodyRHOA 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1C1 unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 100-150) antibodyRHOA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (C-Term) antibodyRHOA 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (pSer188) antibodyRHOA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-194) antibodyRHOA 适用: 人 WB, ELISA, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 1B12 unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (C-Term) antibodyRHOA 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-193) antibodyKO Validated RHOA 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-191) antibodyRHOA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-193) antibodyRHOA 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:5000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RHOA (Ras Homolog Gene Family, Member A (RHOA))
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别名
- RHOA
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背景
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Background: Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Stimulates PKN2 kinase activity. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization (By similarity). Regulates KCNA2 potassium channel activity by reducing its location at the cell surface in response to CHRM1 activation, promotes KCNA2 endocytosis (PubMed:9635436, PubMed:19403695).
Aliases: Transforming protein RhoA (Rho cDNA clone 12) (h12), RHOA, ARH12 ARHA RHO12
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UniProt
- P61586
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途径
- Microtubule Dynamics, WNT signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interactome
抗原
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