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ZBED1 抗体

ZBED1 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7127132
发货至: 中国
  • 抗原 See all ZBED1 抗体
    ZBED1 (Zinc Finger, BED-Type Containing 1 (ZBED1))
    适用
    • 33
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    • 1
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    宿主
    • 25
    • 8
    小鼠
    克隆类型
    • 27
    • 6
    单克隆
    标记
    • 20
    • 3
    • 2
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    • 1
    • 1
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    This ZBED1 antibody is un-conjugated
    应用范围
    • 21
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    • 10
    • 7
    • 3
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    • 1
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    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    特异性
    ZBED1 (zinc finger BED domain-containing protein 1), also known as ALTE (Ac-like transposable element), DREF or TRAMP, is a 694 amino acid protein that localizes specifically to granular structures within the nucleus. Expressed ubiquitously at low levels and present at higher levels in heart, placenta, spleen and skeletal muscle, ZBED1 is thought to function as a transcription factor that regulates a number of ribosomal protein (RP) encoding genes, thereby playing a role in the cell cycle and in cell proliferation events. ZBED1 contains one BED-type zinc finger and binds specifically to 5'- TGTCG[CT]GA[CT]A-3' DNA regions found in RP promotors. Additionally, ZBED1 binds strongly to the promotor region of Histone H1 (a protein required for the condensation of nucleosomes into higher order structures), subsequently activating H1 transcription.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human ZBED1 protein
    亚型
    IgG2a
    Top Product
    Discover our top product ZBED1 Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or HepG2 cells.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    ZBED1 (Zinc Finger, BED-Type Containing 1 (ZBED1))
    别名
    ZBED1 (ZBED1 产品)
    别名
    ZBED1 antibody, ZBED1P antibody, ALTE antibody, DREF antibody, TRAMP antibody, hDREF antibody, zinc finger BED-type containing 1 antibody, zinc finger, BED-type containing 1 antibody, ZBED1 antibody, zbed1 antibody
    背景
    Ac like transposable element, ALTE, BED type zinc finger domain containing protein 1, DNA replication related element binding factor, dREF homolog, hDREF, KIAA0785, Putative Ac-like transposable element, TRAMP, ZBED1, Zinc finger BED domain-containing protein 1,ZBED1 / DREF
    Cellular localisation: Nucleus. In granular structures.
    分子量
    86kDa
    基因ID
    9189, 131452
    UniProt
    O96006
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