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NR1H2 抗体

NR1H2 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7127043
发货至: 中国
  • 抗原 See all NR1H2 抗体
    NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))
    适用
    • 33
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    宿主
    • 46
    • 2
    • 1
    小鼠
    克隆类型
    • 47
    • 2
    单克隆
    标记
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    This NR1H2 antibody is un-conjugated
    应用范围
    • 43
    • 18
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    ELISA, Coating (Coat)
    特异性
    The liver X receptors, LXRA (NR1H3) and LXRB (NR1H2) form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements. LXRB can inhibit proliferation and induce apoptosis of cancer cells.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human NR1H2 (LXRB) protein
    亚型
    IgG2
    Top Product
    Discover our top product NR1H2 Primary Antibody
  • 应用备注

    Known_Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa, SW480 or A549 cells. Liver.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))
    别名
    NR1H2 (NR1H2 产品)
    别名
    NR1H2 antibody, lxr-b antibody, lxrb antibody, ner antibody, ner-i antibody, rip15 antibody, unr antibody, DKFZp468A0622 antibody, AI194859 antibody, LXR antibody, LXRB antibody, LXRbeta antibody, NER1 antibody, OR-1 antibody, RIP15 antibody, UR antibody, Unr antibody, Unr2 antibody, LXR-b antibody, NER antibody, NER-I antibody, UNR antibody, nuclear receptor subfamily 1 group H member 2 antibody, nuclear receptor subfamily 1, group H, member 2 antibody, nuclear receptor subfamily 1 group H member 2 L homeolog antibody, NR1H2 antibody, nr1h2 antibody, Nr1h2 antibody, nr1h2.L antibody
    背景
    Liver X nuclear receptor beta, Liver X receptor beta, LX receptor beta, LXR beta, LXRB, NER1, Nuclear orphan receptor LXR beta, Nuclear receptor NER, Nuclear receptor subfamily 1 group H member 2 (NR1H2), OR-1, Oxysterols receptor LXR-beta, RIP15, Steroid hormone nuclear receptor NER, Ubiquitously-expressed nuclear receptor (UNR),Liver X Receptor beta (LXRB) (Orphan Receptor)
    Cellular localisation: Nuclear
    分子量
    56kDa
    基因ID
    7376, 432976
    UniProt
    P55055
    途径
    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding
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