Recombinant LEF1 抗体 (AA 100-200)
-
- 抗原 See all LEF1 抗体
- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
- 抗体类型
- Recombinant Antibody
-
抗原表位
- AA 100-200
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This LEF1 antibody is un-conjugated
-
应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Lymphoid Enhancing Factor 1 (LEF1) is a transcription factor that belongs to the TCF/LEF family. LEF1 participates as a regulator in Wnt signaling pathways. LEF1 is an important factor in lymphopoiesis and is expressed normally in T and pro-B cells but not expressed in mature B cells. Anti-LEF1 may be used as an aid for differentiation of chronic lymphocytic leukemia/small lymphocytic lymphoma from other small B cell lymphomas.
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant fragment (around aa100-200) of human LEF1 protein (exact sequence is proprietary)
- 亚型
- IgG1
- Top Product
- Discover our top product LEF1 Primary Antibody
-
-
- 应用备注
-
Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human tonsil and thymus.
- 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
-
- 抗原
- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
- 别名
- LEF1 (LEF1 产品)
- 背景
-
Lymphoid enhancer-binding factor 1 (LEF1), T cell specific transcription factor 1 alpha (TCF1a), TCF1 alpha, TCF10, TCF7L3, Transcription factor T cell specific 1 alpha,LEF1 / TCF1 alpha (Transcription Factor)
Cellular localisation: Nucleus. - 分子量
- 44kDa
- 基因ID
- 51176, 726506
- UniProt
- Q9UJU2
- 途径
- WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
-