ATF2 抗体
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北京 101111
Quick Overview for ATF2 抗体 (ABIN7126255)
抗原
See all ATF2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- ATF2 Antibody
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特异性
- This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene.
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交叉反应 （详细）
- Human. Predicted to react in mouse and rat.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human ATF2 protein
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亚型
- IgG2b
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anti-Activating Transcription Factor 2 (ATF2) (AA 1-190) antibody
ATF2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 2 (ATF2) (AA 93-450) antibodyATF2 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 2 (ATF2) (C-Term) antibodyATF2 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 2 (ATF2) antibodyATF2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 4F12 unconjugated
anti-Activating Transcription Factor 2 (ATF2) (pThr73) antibodyATF2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 2 (ATF2) (AA 1-209) antibodyATF2 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-Activating Transcription Factor 2 (ATF2) (AA 91-190) antibodyATF2 适用: 人 IF, PLA 宿主: 小鼠 Monoclonal 1C2 unconjugated
anti-Activating Transcription Factor 2 (ATF2) antibodyATF2 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 4C12 unconjugated
anti-Activating Transcription Factor 2 (ATF2) (pThr51), (pThr53) antibodyATF2 适用: 小鼠 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 2 (ATF2) (AA 401-450) antibodyATF2 适用: 人, 小鼠, 大鼠, 小鸡, 猴, Cow, 兔, 马, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or U87 cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- ATF2 (Activating Transcription Factor 2 (ATF2))
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别名
- ATF2
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背景
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HB16, CREB2, TREB7, CREB-2, CRE-BP1
HeLa or U87 cells.
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分子量
- 54.5kDa
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基因ID
- 1386, 592510
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UniProt
- P15336
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途径
- MAPK Pathway, RTK signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
抗原
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