SARS-CoV-2 Spike 抗体
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- 抗原 See all SARS-CoV-2 Spike 抗体
- SARS-CoV-2 Spike
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适用
- SARS-CoV-2
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SARS-CoV-2 Spike antibody is un-conjugated
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应用范围
- ELISA
- 原理
- SARS-CoV-2 Whole Spike Protein Antibody
- 特异性
- Anti-SARS-CoV-2 Whole Spike antibody is directed against SARS Coronavirus 2 Spike (S) protein.
- 交叉反应 (详细)
- No reactivity was seen against SARS COV-2 Spike S1 subunit, SARS COV-2 Spike S1 RBD, SARS COV-2 loop, SARS COV-2 (N), MERS CoV. Cross reactivity with homologues from other sources has not been determined.
- 纯化方法
- The product was purified from roller bottle culture by protein A chromatography. BLAST analysis was used to suggest reactivity with related Coronavirus proteins.
- 过滤
- Sterile filtered
- 免疫原
- This protein A purified antibody was produced by repeated immunizations with a purified SARS-CoV-2 S protein with His-tag, derived from the transfected human HEK293 cells.
- 克隆位点
- 15D9-E2-C10
- 亚型
- IgG
- Top Product
- Discover our top product SARS-CoV-2 Spike Primary Antibody
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- 应用备注
- Anti-SARS-CoV-2 Whole Spike protein antibody has been tested for use in ELISA and shows reactivity to SARS COV-2 Whole Spike and COV-2 Spike (S2) protein. Specific conditions for reactivity should be optimized by the end user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- SARS-CoV-2 Spike
- Abstract
- SARS-CoV-2 Spike 产品
- 别名
- E2 antibody, E2 glycoprotein precursor antibody, Surface Glycoprotein antibody, S antibody
- 物质类
- Viral Protein
- 背景
- SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) the virus that causes the disease COVID-19, is related to SARS-CoV, MERS-CoV, and other betacoronaviruses (HKU1, NL63, OC43 and 229E). SARS-CoV-2 is an enveloped positive strand RNA virus that consists of several structural proteins including spike (S) protein, envelope (E) protein, membrane (M) protein and nucleocapsid (N) protein; and other non-structural proteins (NSPs). Spike proteins located on the surface of the virus, have a high affinity for binding to human receptor ACE2 (angiotensin-converting enzyme 2) within respiratory epithelial which serves as an entry mechanism for infection. As such, the S protein may be vital to blocking viral infection and vaccine development.
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