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FAS 抗体 (AA 156-335)

This anti-FAS antibody is a 小鼠 单克隆 antibody detecting FAS in WB, FACS, IHC 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7119981
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FAS 抗体 (AA 156-335) (ABIN7119981)

抗原

See all FAS 抗体
FAS (TNF Receptor Superfamily, Member 6 (FAS))

适用

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  • 62
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  • 1
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  • 1
人, 小鼠

宿主

  • 176
  • 119
  • 9
  • 6
  • 1
  • 1
小鼠

克隆类型

  • 162
  • 148
  • 1
单克隆

标记

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  • 28
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  • 15
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  • 7
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This FAS antibody is un-conjugated

应用范围

  • 175
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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA

克隆位点

4B6
  • 抗原表位

    • 25
    • 16
    • 16
    • 13
    • 9
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    • 7
    • 6
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    • 1
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    AA 156-335

    原理

    FAS antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 156-335aa

    Immunogen: Fas(TNF receptor superfamily, member 6)

    亚型

    IgG2a
  • 应用备注

    WB: 1:1000-1:8000, IHC: 1:50-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    FAS (TNF Receptor Superfamily, Member 6 (FAS))

    别名

    FAS

    背景

    Synonyms: Tumor necrosis factor receptor superfamily member 6|Apo-1 antigen|Apoptosis-mediating surface antigen FAS|FASLG receptor|FAS|APT1|FAS1|TNFRSF6

    Background: Fas(CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor(TNF) receptor superfamily. It can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex(DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form(40-55 kDa) of Fas is due to glycosylation.

    分子量

    38-45 kDa

    基因ID

    355

    UniProt

    P25445

    途径

    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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