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SS18L1 抗体

SS18L1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 小鼠 Monoclonal 7A7 unconjugated
产品编号 ABIN7119693
发货至: 中国
  • 抗原 See all SS18L1 抗体
    SS18L1 (Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1))
    适用
    • 27
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 27
    小鼠
    克隆类型
    • 27
    单克隆
    标记
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    This SS18L1 antibody is un-conjugated
    应用范围
    • 22
    • 18
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Protein A+G purification
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    synovial sarcoma translocation gene on chromosome 18-like 1
    克隆位点
    7A7
    亚型
    IgG1
    Top Product
    Discover our top product SS18L1 Primary Antibody
  • 应用备注
    WB: 1:1000-1:6000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    SS18L1 (Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1))
    别名
    CREST (SS18L1 产品)
    别名
    crest antibody, CREST antibody, LP2261 antibody, A230053O16Rik antibody, SS18L1, nBAF chromatin remodeling complex subunit antibody, synovial sarcoma translocation gene on chromosome 18-like 1 antibody, synovial sarcoma translocation gene on chromosome 18-like 1 S homeolog antibody, SS18, nBAF chromatin remodeling complex subunit like 1 antibody, SS18L1 antibody, ss18l1 antibody, ss18l1.S antibody, Ss18l1 antibody
    背景
    Synonyms:CREST, KIAA0693, LP2261, SS18 like protein 1, SS18L1, SYT homolog 1 Background:Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein(CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP(By similarity).
    分子量
    50 kDa
    UniProt
    O75177
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