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KLHL22 抗体

KLHL22 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7115599
发货至: 中国
  • 抗原 See all KLHL22 抗体
    KLHL22 (Kelch-Like 22 (KLHL22))
    适用
    • 33
    • 33
    • 17
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 38
    • 10
    克隆类型
    • 39
    • 9
    多克隆
    标记
    • 13
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This KLHL22 antibody is un-conjugated
    应用范围
    • 37
    • 22
    • 13
    • 13
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    kelch-like 22(Drosophila)
    亚型
    IgG
    Top Product
    Discover our top product KLHL22 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    KLHL22 (Kelch-Like 22 (KLHL22))
    别名
    KLHL22 (KLHL22 产品)
    别名
    2610318I18Rik antibody, Kelchl antibody, KELCHL antibody, RGD1306288 antibody, kelch-like 22 antibody, kelch like family member 22 antibody, kelch-like family member 22 antibody, Klhl22 antibody, KLHL22 antibody
    背景
    Synonyms: Background:Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint(SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation.
    分子量
    72 kDa
    基因ID
    84861
    UniProt
    Q53GT1
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