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IL-17 抗体

IL17 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5E2 unconjugated
产品编号 ABIN7115424
发货至: 中国
  • 抗原 See all IL-17 (IL17) 抗体
    IL-17 (IL17) (Interleukin 17 (IL17))
    适用
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    宿主
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    小鼠
    克隆类型
    • 72
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    单克隆
    标记
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    This IL-17 antibody is un-conjugated
    应用范围
    • 90
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    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    纯化方法
    Protein A+G purification
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    interleukin 17A
    克隆位点
    5E2
    亚型
    IgG1
    Top Product
    Discover our top product IL17 Primary Antibody
  • 应用备注
    WB: 1:500-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    IL-17 (IL17) (Interleukin 17 (IL17))
    别名
    IL-17 (IL17 产品)
    别名
    CTLA8 antibody, IL-17 antibody, IL-17A antibody, IL17 antibody, Ctla-8 antibody, Ctla8 antibody, Il17 antibody, ChIL-17 antibody, IL-17F antibody, IL17A antibody, CTLA-8 antibody, interleukin 17A antibody, IL17A antibody, Il17a antibody
    背景
    Synonyms:CTLA 8, CTLA8, IL 17, IL 17A, IL17, IL-17, IL17A, interleukin 17A Background:IL17A, also named as IL-17, is a proinflammatory cytokine. IL-17, synthesized only by memory T cells and natural killer cells, has pleiotropic effects, mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2(PTGS2/COX-2), as well as enhance the production of nitric oxide(NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein, that is widely expressed on epithelial cells, fibroblasts, B and T cells, and monocytic cells. In psoriatic skin lesions, both Th17 cells and their downstream effector molecules, e.g. IL-17 and IL-22, are highly increased.
    分子量
    18 kDa
    基因ID
    3605
    UniProt
    Q16552
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