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GSDMD 抗体

GSDMD 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7114492
发货至: 中国
  • 抗原 See all GSDMD 抗体
    GSDMD (Gasdermin D (GSDMD))
    适用
    人, 大鼠, 小鼠
    宿主
    • 17
    • 4
    克隆类型
    • 16
    • 5
    多克隆
    标记
    • 17
    • 2
    • 1
    • 1
    This GSDMD antibody is un-conjugated
    应用范围
    • 16
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    gasdermin D
    亚型
    IgG
    Top Product
    Discover our top product GSDMD Primary Antibody
  • 应用备注
    WB: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    GSDMD (Gasdermin D (GSDMD))
    别名
    GSDMD (GSDMD 产品)
    别名
    GSDMDC1 antibody, GSDMD antibody, DF5L antibody, DFNA5L antibody, 1810036L03Rik antibody, AW558049 antibody, Dfna5l antibody, Gsdmdc1 antibody, M2-4 antibody, gasdermin D antibody, GSDMD antibody, Gsdmd antibody
    背景
    Synonyms:DF5L, DFNA5L, FKSG10, FLJ12150, gasdermin D, GSDMD, GSDMDC1 Background:GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
    分子量
    50-53 kDa
    基因ID
    79792
    UniProt
    P57764
    途径
    Inflammasome
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