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Connexin 43/GJA1 抗体

This anti-Connexin 43/GJA1 antibody is a 兔 多克隆 antibody detecting Connexin 43/GJA1 in WB, IHC, ELISA, IP 和 FACS. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7114478
发货至: 中国

Quick Overview for Connexin 43/GJA1 抗体 (ABIN7114478)

抗原

See all Connexin 43/GJA1 (GJA1) 抗体
Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

适用

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人, 大鼠, 小鼠

宿主

  • 132
  • 8
  • 3
  • 2

克隆类型

  • 135
  • 9
多克隆

标记

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This Connexin 43/GJA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS)
  • 原理

    GJA1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    gap junction protein, alpha 1, 43kDa

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:50-1:200, IF: 1:50-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

    别名

    GJA1

    背景

    Synonyms: Gap junction alpha-1 protein|Connexin-43 (Cx43)|Gap junction 43 kDa heart protein|GJA1|GJAL

    Background: Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract(By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles(By similarity).

    分子量

    47 kDa

    UniProt

    P17302

    途径

    MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
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