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Fibrinogen beta Chain 抗体

FGB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6F4 unconjugated
产品编号 ABIN7114194
发货至: 中国
  • 抗原 See all Fibrinogen beta Chain (FGB) 抗体
    Fibrinogen beta Chain (FGB)
    适用
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    宿主
    • 55
    • 13
    • 1
    小鼠
    克隆类型
    • 56
    • 13
    单克隆
    标记
    • 36
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    This Fibrinogen beta Chain antibody is un-conjugated
    应用范围
    • 50
    • 26
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    Western Blotting (WB), ELISA
    纯化方法
    Protein A+G purification
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    fibrinogen beta chain
    克隆位点
    6F4
    亚型
    IgG2a
    Top Product
    Discover our top product FGB Primary Antibody
  • 应用备注
    WB: 1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    Fibrinogen beta Chain (FGB)
    别名
    FGB (FGB 产品)
    别名
    FGB antibody, 2510049G14Rik antibody, DKFZp470D0312 antibody, LOC100223598 antibody, fibrinogen antibody, Ab1-216 antibody, Ac1-581 antibody, wu:fa55c11 antibody, zgc:77116 antibody, fgb antibody, fibrinogen beta chain antibody, fibrinogen beta chain L homeolog antibody, FGB antibody, Fgb antibody, fgb antibody, fgb.L antibody
    背景
    Synonyms:FGB, fibrinogen beta chain Background:Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha(FGA) and fibrinogen gamma(FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
    分子量
    50 kDa
    基因ID
    2244
    UniProt
    P02675
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