电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

BAX 抗体 (AA 1-192)

This anti-BAX antibody is a 兔 多克隆 antibody detecting BAX in WB, IHC, ELISA, FACS 和 IP. Suitable for 人, 小鼠, 大鼠, 兔 和 绵羊.
产品编号 ABIN7111962
发货至: 中国

Quick Overview for BAX 抗体 (AA 1-192) (ABIN7111962)

抗原

See all BAX 抗体
BAX (BCL2-Associated X Protein (BAX))

适用

  • 232
  • 148
  • 131
  • 45
  • 31
  • 25
  • 23
  • 18
  • 16
  • 10
  • 8
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 兔, 绵羊

宿主

  • 151
  • 94
  • 3
  • 1

克隆类型

  • 161
  • 88
多克隆

标记

  • 127
  • 13
  • 11
  • 9
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BAX antibody is un-conjugated

应用范围

  • 217
  • 88
  • 77
  • 64
  • 52
  • 52
  • 45
  • 41
  • 33
  • 17
  • 11
  • 8
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP)
  • 抗原表位

    • 32
    • 26
    • 18
    • 17
    • 15
    • 11
    • 10
    • 9
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-192

    原理

    BAX antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 1-192aa

    Immunogen: BCL2-associated X protein

    亚型

    IgG
  • 应用备注

    WB: 1:1000-1:10000, IP: 1:1000-1:10000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    BAX (BCL2-Associated X Protein (BAX))

    别名

    BAX

    背景

    Synonyms: Apoptosis regulator BAX|Bcl-2-like protein 4 (Bcl2-L-4)|BAX|BCL2L4

    Background: BAX, also named as BCL2L4, is a pro-apoptotic member of the Bcl-2 protein family, which plays a pivotal role in controlling cell life and death. Bax largely localizes to the cytoplasm of healthy cells, but accumulates on the outer mitochondrial membrane upon apoptosis induction(PMID: 9108035). BAX can commit a cell to apoptosis by translocation from the cytosol to the mitochondria and permeabilization of the outer mitochondrial membrane, which leads to the release of cytochrome c from mitochondria(PMID: 21763611). The expression of BAX is upregulated by the tumor suppressor protein p53, and BAX has been shown to be involved in p53-mediated apoptosis(PMID: 8183579).

    分子量

    21 kDa

    基因ID

    581

    UniProt

    Q07812

    途径

    p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
You are here:
Chat with us!