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BAX 抗体 (AA 1-192)

This anti-BAX antibody is a 小鼠 单克隆 antibody detecting BAX in WB, IHC, ELISA 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7111961
发货至: 中国

Quick Overview for BAX 抗体 (AA 1-192) (ABIN7111961)

抗原

See all BAX 抗体
BAX (BCL2-Associated X Protein (BAX))

适用

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人, 小鼠, 大鼠

宿主

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小鼠

克隆类型

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  • 87
单克隆

标记

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This BAX antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

克隆位点

5F4
  • 抗原表位

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    AA 1-192

    原理

    BAX antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 1-192aa

    Immunogen: BCL2-associated X protein

    亚型

    IgG2a
  • 应用备注

    WB: 1:1000-1:10000, IHC: 1:400-1:1000, IF: 1:50-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    BAX (BCL2-Associated X Protein (BAX))

    别名

    BAX

    背景

    Synonyms: Apoptosis regulator BAX|Bcl-2-like protein 4 (Bcl2-L-4)|BAX|BCL2L4

    Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

    分子量

    21 kDa

    基因ID

    581

    UniProt

    Q07812

    途径

    p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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