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BARD1 抗体 (AA 101-200) (HRP)

This anti-BARD1 antibody is a 兔 多克隆 antibody detecting BARD1 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN706505
发货至: 中国

Quick Overview for BARD1 抗体 (AA 101-200) (HRP) (ABIN706505)

抗原

See all BARD1 抗体
BARD1 (BRCA1 Associated RING Domain 1 (BARD1))

适用

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宿主

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克隆类型

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多克隆

标记

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This BARD1 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 101-200

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human BARD1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    BARD1 (BRCA1 Associated RING Domain 1 (BARD1))

    别名

    BARD1

    背景

    Synonyms: BRCA1-associated RING domain protein 1, BARD-1, BARD1

    Background: Probable E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage.

    基因ID

    580

    UniProt

    Q99728

    途径

    DNA Damage Repair
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