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Girdin 抗体 (pSer1765)

The 兔 单克隆 anti-Girdin antibody is suitable to detect Girdin in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7091890
发货至: 中国
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Quick Overview for Girdin 抗体 (pSer1765) (ABIN7091890)

抗原

See all Girdin (CCDC88A) 抗体
Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

适用

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宿主

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克隆类型

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单克隆

标记

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This Girdin antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

G5F7
  • 抗原表位

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    pSer1765

    预测反应

    Human,Mouse,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthesised phosphopeptide derived from human APE around the phosphorylation site of Ser1765

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

    别名

    Girdin

    背景

    Synonyms: GIV (pY1765), Girdin (phospho Y1765), p-Girdin (phospho Y1765), Akt phosphorylation enhancer, APE, Coiled coil domain containing protein 88A, G alpha interacting vesicle associated protein, Girders of actin filament, GIV, HkRP1, Hook related protein 1, AKT iphosphorylation enhancer, Akt phosphorylation enhancer, Ccdc88a, GIV, GRDN, GRDN_HUMAN, HkRP1, Hook related protein 1, Hook-related protein 1, KIAA1212.

    Background: This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

    基因ID

    55704

    UniProt

    Q3V6T2
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