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TBP 抗体 (HRP)

This anti-TBP antibody is a 小鼠 单克隆 antibody detecting TBP in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7091718
发货至: 中国

Quick Overview for TBP 抗体 (HRP) (ABIN7091718)

抗原

See all TBP 抗体
TBP (TATA Box Binding Protein (TBP))

适用

  • 95
  • 47
  • 44
  • 6
  • 6
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  • 5
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  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 64
  • 34
  • 2
小鼠

克隆类型

  • 61
  • 39
单克隆

标记

  • 69
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TBP antibody is conjugated to HRP

应用范围

  • 82
  • 30
  • 30
  • 25
  • 25
  • 14
  • 14
  • 13
  • 11
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

6G8
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein G.

    免疫原

    Recombinant human TBP protein

    亚型

    IgG
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • 抗原

    TBP (TATA Box Binding Protein (TBP))

    别名

    TATA binding protein TBP/TBP

    背景

    Synonyms: GTF2D, TFIID, GTF2D1, MGC117320, MGC126054, MGC126055, SCA 17, SCA17, TATA binding factor, TATA box binding protein, TATA box factor, TATA sequence binding protein, TATA sequence-binding protein, TATA binding protein TBP, TATA-binding factor, TATA-box factor, TATA-box-binding protein, TBP, TBP_HUMAN, TF2D, TFIID, Transcription initiation factor TFIID TBP subunit.

    Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010]

    基因ID

    6908

    UniProt

    P20226

    途径

    WNT signaling
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