MGMT 抗体 (AA 1-100) (HRP)
Quick Overview for MGMT 抗体 (AA 1-100) (HRP) (ABIN7091487)
抗原
See all MGMT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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交叉反应
- 大鼠
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预测反应
- Human,Mouse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from mouse MGMT
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亚型
- IgG
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
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别名
- MGMT
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背景
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Synonyms: 6 O methylguanine DNA methyltransferase, Agat, AGT, AI267024, EC 2.1.1.63, Methylated DNA protein cysteine methyltransferase, Methylguanine DNA methyltransferase, MGC107020, MGMT: O-6 methylguanine DNA methyltransferase, O 6 methylguanine DNA alkyltransferase, O 6 methylguanine DNA methyltransferase, O-6 methylguanine DNA alkyltransferase, O-6-methylguanine-DNA methyltransferase, O6 methylguanine DNA methyltransferase, MGMT_HUMAN.
Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
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基因ID
- 17314
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UniProt
- P26187
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途径
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
抗原
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