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NLRP3 抗体 (AA 501-600) (HRP)

This anti-NLRP3 antibody is a 兔 多克隆 antibody detecting NLRP3 in ELISA, IHC (p) 和 IHC (fro). Suitable for 人, 小鼠, 大鼠 和 兔.
产品编号 ABIN7091467
发货至: 中国

Quick Overview for NLRP3 抗体 (AA 501-600) (HRP) (ABIN7091467)

抗原

See all NLRP3 抗体
NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

适用

  • 75
  • 32
  • 17
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 兔

宿主

  • 74
  • 12
  • 2
  • 1

克隆类型

  • 68
  • 21
多克隆

标记

  • 57
  • 8
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This NLRP3 antibody is conjugated to HRP

应用范围

  • 56
  • 41
  • 17
  • 14
  • 10
  • 9
  • 6
  • 6
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 10
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 501-600

    交叉反应

    人, 小鼠, 兔, 大鼠

    预测反应

    Dog,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human NALP3/CIAS1

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • 抗原

    NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

    别名

    NALP3/CIAS1

    背景

    Synonyms: LRR and PYD domains-containing protein 3, AGTAVPRL, AII/AVP antibody Angiotensin/vasopressin receptor AII/AVP like, Angiotensin/vasopressin receptor AII/AVP-like, C1orf7, Caterpiller protein 1.1, CIAS 1, CIAS1, CLR1.1, Cold autoinflammatory syndrome 1, Cold autoinflammatory syndrome 1 protein, Cryopyrin, Familial cold autoinflammatory syndrome, FCAS, FCU, Muckle-Wells syndrome, MWS, NACHT, NACHT LRR and PYD containing protein 3, NALP 3, NALP3, NALP3_HUMAN, NLRP3, PYPAF 1, PYPAF1 antibody PYRIN containing APAF1 like protein 1, PYRIN-containing APAF1-like protein 1.

    Background: May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.

    基因ID

    114548

    UniProt

    Q96P20

    途径

    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
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