ROS1 抗体
Quick Overview for ROS1 抗体 (ABIN7090797)
抗原
See all ROS1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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预测反应
- Human
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免疫原
- Recombinant human ROS1.
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
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别名
- ROS1
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背景
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Synonyms: ROS, ros protein, c ros, c-ros, c ros1, MCF3, Oncogene ROS, OTTHUMP00000040389, Proto oncogene c ros 1 protein, Proto oncogene tyrosine protein kinase ROS, Proto oncogene tyrosine protein kinase ROS precursor, Ros1, ROS1C, Transmembrane tyrosine specific protein kinase, v ros avian UR2 sarcoma virus oncogene homolog 1, v ros UR2 sarcoma virus oncogene homolog 1, ROS1_HUMAN, Proto-oncogene tyrosine-protein kinase ROS, Proto-oncogene c-Ros, Proto-oncogene c-Ros-1, Receptor tyrosine kinase c-ros oncogene 1, c-Ros receptor tyrosine kinase
Background: Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.
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基因ID
- 6098
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UniProt
- P08922
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途径
- RTK signaling
抗原
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