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ROS1 抗体

This anti-ROS1 antibody is a 小鼠 单克隆 antibody detecting ROS1 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN7090797
发货至: 中国

Quick Overview for ROS1 抗体 (ABIN7090797)

抗原

See all ROS1 抗体
ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))

适用

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宿主

  • 48
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  • 1
小鼠

克隆类型

  • 48
  • 10
单克隆

标记

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This ROS1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

F7Y3
  • 预测反应

    Human

    免疫原

    Recombinant human ROS1.
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 浓度

    0.5 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))

    别名

    ROS1

    背景

    Synonyms: ROS, ros protein, c ros, c-ros, c ros1, MCF3, Oncogene ROS, OTTHUMP00000040389, Proto oncogene c ros 1 protein, Proto oncogene tyrosine protein kinase ROS, Proto oncogene tyrosine protein kinase ROS precursor, Ros1, ROS1C, Transmembrane tyrosine specific protein kinase, v ros avian UR2 sarcoma virus oncogene homolog 1, v ros UR2 sarcoma virus oncogene homolog 1, ROS1_HUMAN, Proto-oncogene tyrosine-protein kinase ROS, Proto-oncogene c-Ros, Proto-oncogene c-Ros-1, Receptor tyrosine kinase c-ros oncogene 1, c-Ros receptor tyrosine kinase

    Background: Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.

    基因ID

    6098

    UniProt

    P08922

    途径

    RTK signaling
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