FCGR2B 抗体 (Extracellular Domain) (FITC)
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- 抗原 See all FCGR2B 抗体
- FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))
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抗原表位
- Extracellular Domain
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FCGR2B antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 产品特性
- The clone 4F5, a mouse monoclonal antibody recognizes anti- FcγRIIb, a cell surface protein also known as CD32b. FcγRII has two major isoforms named FcγRIIa and FcγRIIb with high degree of homology. The clone 4F5 selectively reacts with FcγRIIb but not with FcγRIIa. The CD32b antigen is widely expressed on the cell surface of circulating B lymphocytes, monocytes, neutrophils, myeloid dendritic cells (DCs), platelets and at very low levels on plasmacytoid DCs. FcγRs (FcγRI/CD64, FcγRII/CD32, FcγRIII/CD16, and FcγRIV/CD16-2) play important roles in inflammatory cell activation, clearance, presentation of Ag, and maintenance of IgG homeostasis. Published reports claimed that 4F5 partially blocks the ligand-binding of FcRIIb and mediates an inhibitory signal by co-cross-linking FcRIIb with activating FcRs. Clone 4F5 supports study of the expression, regulation, and function of FcγRIIb and may be useful in the area of therapeutic applications where the modulation of FcγRIIb is required.
- 纯化方法
- Purified
- 纯度
- >95 %
- 质量等级
- GMP Grade
- 免疫原
- Recombinant human FcgammaRIIb/c (CD32b) extracellular domain
- 克隆位点
- 4F5
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product FCGR2B Primary Antibody
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anti-Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) (pTyr292) antibody
FCGR2B 适用: 人, 小鼠, 猴 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) (AA 45-154) antibodyFCGR2B 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) (C-Term) antibodyVerified FCGR2B 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) (AA 12-289) antibodyFCGR2B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) (AA 1-310) antibodyFCGR2B 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) (AA 1-310) antibodyFCGR2B 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) (C-Term) antibodyFCGR2B 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) (C-Term) antibodyFCGR2B 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) (C-Term) antibodyFCGR2B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) (pTyr292) antibodyFCGR2B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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- 抗原
- FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))
- 别名
- CD32b (FCGR2B 产品)
- 别名
- CD32 antibody, CD32B antibody, FCG2 antibody, FCGR2 antibody, IGFR2 antibody, FCGR2B antibody, AI528646 antibody, F630109E10Rik antibody, Fc[g]RII antibody, FcgRII antibody, Fcgr2 antibody, Fcgr2a antibody, Fcr-2 antibody, Fcr-3 antibody, Ly-17 antibody, Ly-m20 antibody, LyM-1 antibody, Lym-1 antibody, FCRII antibody, FcRII antibody, Fc fragment of IgG receptor IIb antibody, Fc fragment of IgG, low affinity IIb, receptor (CD32) antibody, Fc receptor, IgG, low affinity IIb antibody, low affinity immunoglobulin gamma Fc region receptor II antibody, FCGR2B antibody, Fcgr2b antibody, LOC100856270 antibody
- 背景
- The clone 4F5, a mouse monoclonal antibody recognizes anti- FcγRIIb, a cell surface protein also known as CD32b. FcγRII has two major isoforms named FcγRIIa and FcγRIIb with high degree of homology. The clone 4F5 selectively reacts with FcγRIIb but not with FcγRIIa. The CD32b antigen is widely expressed on the cell surface of circulating B lymphocytes, monocytes, neutrophils, myeloid dendritic cells (DCs), platelets and at very low levels on plasmacytoid DCs. FcγRs (FcγRI/CD64, FcγRII/CD32, FcγRIII/CD16, and FcγRIV/CD16-2) play important roles in inflammatory cell activation, clearance, presentation of Ag, and maintenance of IgG homeostasis. Published reports claimed that 4F5 partially blocks the ligand-binding of FcRIIb and mediates an inhibitory signal by co-cross-linking FcRIIb with activating FcRs. Clone 4F5 supports study of the expression, regulation, and function of FcγRIIb and may be useful in the area of therapeutic applications where the modulation of FcγRIIb is required.
- 基因ID
- 2213
- UniProt
- P31994
- 途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, BCR Signaling
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