THEM4 抗体
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- 抗原 See all THEM4 抗体
- THEM4 (Thioesterase Superfamily Member 4 (THEM4))
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This THEM4 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 大鼠
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein corresponding to Mouse THEM4
- Top Product
- Discover our top product THEM4 Primary Antibody
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anti-Thioesterase Superfamily Member 4 (THEM4) (AA 1-240) antibody
THEM4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Thioesterase Superfamily Member 4 (THEM4) (AA 37-150) antibodyTHEM4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioesterase Superfamily Member 4 (THEM4) (Center) antibodyTHEM4 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC/IF (M,R) 1:200-1:400/1:200-1:400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- THEM4 (Thioesterase Superfamily Member 4 (THEM4))
- 别名
- THEM4 (THEM4 产品)
- 别名
- THEM4 antibody, CTMP antibody, 2700077M13Rik antibody, 4921507I02Rik antibody, RGD1304723 antibody, thioesterase superfamily member 4 antibody, thioesterase superfamily member 4 L homeolog antibody, THEM4 antibody, them4 antibody, Them4 antibody, them4.L antibody
- 背景
- THEM4, also known as CTMP, binds specifically to the carboxy-terminal regulatory domain of PKB/Akt at the plasma membrane and acts as a negative regulator, reversing the phenotype of v-Akt-transformed cells. Hypermethylation of the THEM4 promoter and transcriptional downregulation of the gene has been reported in multiple glioblastomas, suggesting that epigenetic regulation of THEM4 may play a role in the progression of this cancer.
- 基因ID
- 75778
- NCBI登录号
- NP_083707
- UniProt
- Q3UUI3
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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