SIN3A 抗体
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北京 101111
Quick Overview for SIN3A 抗体 (ABIN7075609)
抗原
See all SIN3A 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse mSin3A
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应用备注
- IHC/IF (M,R) 1:100-1:200/1:100-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- SIN3A (SIN3 homolog A, transcription regulator (SIN3A))
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别名
- mSin3A
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背景
- The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex. And It acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation.
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基因ID
- 20466
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NCBI登录号
- NP_001103820
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UniProt
- Q60520
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途径
- Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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