SIN3A 抗体
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- 抗原 See all SIN3A 抗体
- SIN3A (SIN3 homolog A, transcription regulator (SIN3A))
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIN3A antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Immunohistochemistry (IHC)
- 交叉反应
- 大鼠
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein corresponding to Mouse mSin3A
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- 应用备注
- IHC/IF (M,R) 1:100-1:200/1:100-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- SIN3A (SIN3 homolog A, transcription regulator (SIN3A))
- 别名
- mSin3A (SIN3A 产品)
- 背景
- The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex. And It acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation.
- 基因ID
- 20466
- NCBI登录号
- NP_001103820
- UniProt
- Q60520
- 途径
- Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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