P2RY12 抗体
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北京 101111
Quick Overview for P2RY12 抗体 (ABIN7075321)
抗原
See all P2RY12 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse P2Y12
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应用备注
- WB (M,R) 1:250-1:500, IHC/IF (M,R) 1:1000-1:3000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))
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别名
- P2Y12
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背景
- The P2Y receptor family are G protein-coupled receptors which mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C. To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. Human platelets express two G protein-coupled nucleotide receptors, P2Y1 and P2Y12. P2Y12 is a receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. P2Y12 is an integral membrane protein involved in platelet aggregation. It is highly expressed in platelets, with lower levels in the brain, lung, appendix, pituitary and adrenal gland.
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分子量
- 50 kDa
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基因ID
- 70839
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NCBI登录号
- NP_081847
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UniProt
- Q9CPV9
抗原
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