P2RY12 抗体 (Intracellular)
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Quick Overview for P2RY12 抗体 (Intracellular) (ABIN7581937)
抗原
See all P2RY12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 125-142, Intracellular
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原理
- A Rabbit Polyclonal Antibody to P2Y12 Receptor
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序列
- (C)KTTRPFKTSN PKNLLGAK
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特异性
- Intracellular, 2nd cytoplasmic loop
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预测反应
- Rat,mouse - 16,18 amino acid residues identical
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产品特性
- Anti-P2Y12 Receptor Antibody (ABIN7581937) is a highly specific antibody directed against an intracellular epitope of the human P2RY12. The antibody can be used in western blot, immunoprecipitation, indirect flow cytometry, immunohistochemistry and immunocytochemistry applications. It has been designed to recognize P2RY12 from human, rat, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)KTTRPFKTSNPKNLLGAK, corresponding to amino acid residues 125-142 of human P2RY12
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亚型
- IgG
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anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) antibody
P2RY12 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 1C2A9 unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (AA 141-240) antibodyP2RY12 适用: 人, 小鼠 WB, ELISA, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) antibodyP2RY12 适用: 小鼠 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) antibodyP2RY12 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (AA 270-282), (Extracellular) antibodyP2RY12 适用: 人 WB, LCI, IHC, IF, IC 宿主: 豚鼠 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) antibodyP2RY12 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4970 unconjugated Recombinant Antibody
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (N-Term) antibodyP2RY12 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (Extracellular Domain) antibodyP2RY12 适用: 人, 犬, 猴, 马, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (AA 270-282), (Extracellular) antibodyP2RY12 适用: 人 WB, FACS, LCI, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (AA 270-282), (Extracellular) antibody (Brilliant Violet 421™,Pacific Blue)P2RY12 适用: 人 FACS, LCI 宿主: 兔 Polyclonal Brilliant Violet 421™,Pacific Blue
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))
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别名
- P2RY12
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背景
- P2Y purinoceptor 12, P2RY12, ADP-glucose receptor, Platelet ADP receptor, HORK3,The P2Y receptors belong to the G-protein coupled receptor superfamily. They mediate the actions of the extracellular nucleotides (ATP, ADP, UTP and UDPA). Eight functional mammalian P2Y receptors have been described: P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13, and the UDP-glucose receptor, now renamed P2Y14.1-3 The P2Y12 receptor is co-expressed with P2Y1 receptor on platelets leading to shape change, aggregation, and rise in intracellular Ca2+ upon activation.The only other expression of P2Y12 was found in brain, according to results of reverse transcription-polymerase chain reaction and northern blotting.4 The P2Y12 receptor has become a target for potential therapeutic drugs for the treatment of thromboembolism and other clotting disorders.4
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基因ID
- 64805
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UniProt
- Q9H244
抗原
-
