P2RY12 抗体 (Extracellular)
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北京 101111
Quick Overview for P2RY12 抗体 (Extracellular) (ABIN7581939)
抗原
See all P2RY12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 270-282, Extracellular
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原理
- A Guinea Pig Polyclonal Antibody to P2Y12 Receptor
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序列
- CTAENTLFYV KES
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特异性
- 3rd extracellular loop
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预测反应
- Mouse - 12, rat - 12,13 amino acid residues identical
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产品特性
- Guinea pig Anti-P2Y12 Receptor (extracellular) Antibody (ABIN7581939), formerly ) is a highly specific antibody directed against an epitope of the human P2RY12. The antibody can be used in western blot and live imaging applications. It and has been designed to recognize P2RY12 from mouse, rat, and human samples. The antigen used to immunize guinea pigs is the same as Anti-P2Y12 Receptor (extracellular) Antibody (ABIN7581938) raised in rabbit. Our line of guinea pig antibodies enables more flexibility with our products such as multiplex staining studies, immunoprecipitation, etc.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- CTAENTLFYVKES, corresponding to amino acid residues 270-282 of human P2RY12
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亚型
- IgG
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anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) antibody
P2RY12 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 1C2A9 unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (AA 141-240) antibodyP2RY12 适用: 人, 小鼠 WB, ELISA, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) antibodyP2RY12 适用: 小鼠 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) antibodyP2RY12 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) antibodyP2RY12 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4970 unconjugated Recombinant Antibody
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (N-Term) antibodyP2RY12 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (Extracellular Domain) antibodyP2RY12 适用: 人, 犬, 猴, 马, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (AA 125-142), (Intracellular) antibodyP2RY12 适用: 人 WB, IP, FACS, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (AA 270-282), (Extracellular) antibodyP2RY12 适用: 人 WB, FACS, LCI, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (AA 270-282), (Extracellular) antibody (Brilliant Violet 421™,Pacific Blue)P2RY12 适用: 人 FACS, LCI 宿主: 兔 Polyclonal Brilliant Violet 421™,Pacific Blue
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300
Application Dilutions Western blot wb: 1:400
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))
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别名
- P2RY12
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背景
- P2Y purinoceptor 12, P2RY12, ADP-glucose receptor, Platelet ADP receptor, HORK3,The P2Y receptors belong to the G-protein coupled receptor superfamily. They mediate the actions of the extracellular nucleotides (ATP, ADP, UTP and UDPA). Eight functional mammalian P2Y receptors have been described: P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13, and the UDP-glucose receptor, now renamed P2Y141-3. The P2Y12 receptor is co-expressed with P2Y1 receptor on platelets leading to shape change, aggregation, and rise in intracellular Ca2+ upon activation.The only other expression of P2Y12 was found in brain, according to results of reverse transcription-polymerase chain reaction and northern blotting4. The P2Y12 receptor has become a target for potential therapeutic drugs for the treatment of thromboembolism and other clotting disorders4.
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基因ID
- 64805
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UniProt
- Q9H244
抗原
-
