P2RY12 抗体 (Extracellular) (Brilliant Violet 421™,Pacific Blue)
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Quick Overview for P2RY12 抗体 (Extracellular) (Brilliant Violet 421™,Pacific Blue) (ABIN7582065)
抗原
See all P2RY12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 270-282, Extracellular
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原理
- A Rabbit Polyclonal Antibody to P2Y12 Receptor conjugated to mFluor™ Violet 450 fluorophore
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序列
- CTAENTLFYV KES
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特异性
- 3rd extracellular loop
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预测反应
- Rat,mouse - 12,13 amino acid residues identical.
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产品特性
- Anti-P2Y12 Receptor (extracellular) Antibody (ABIN7581938) is a highly specific antibody directed against an extracellular epitope of the human P2RY12. The antibody can be used in western blot, live cell imaging and indirect flow cytometry applications. It has been designed to recognize P2RY12 from human, rat and mouse samples. Anti-P2Y12 Receptor (extracellular)-mFluor™ Violet 450 Antibody (ABIN7581938)-V) is directly conjugated to mFluor™ Violet 450 fluorophore. This conjugated antibody has been developed to be used in immunofluorescent applications such as direct flow cytometry and live cell imaging. mFluor™ Violet 450 dye has a maximum absorption of 405 nm and maximum emission of 445 nm. These spectral characteristics make it an excellent replacement for Pacific Blue™ or Brilliant Violet™ 421 dyes. For flow cytometry applications, the labeled antibody can be detected using the 405 nm laser lane and a filter set of 450/50.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- CTAENTLFYVKES, corresponding to amino acid residues 270-282 of human P2RY12
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亚型
- IgG
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anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) antibody
P2RY12 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 1C2A9 unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (AA 141-240) antibodyP2RY12 适用: 人, 小鼠 WB, ELISA, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) antibodyP2RY12 适用: 小鼠 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) antibodyP2RY12 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (AA 270-282), (Extracellular) antibodyP2RY12 适用: 人 WB, LCI, IHC, IF, IC 宿主: 豚鼠 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) antibodyP2RY12 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4970 unconjugated Recombinant Antibody
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (N-Term) antibodyP2RY12 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (Extracellular Domain) antibodyP2RY12 适用: 人, 犬, 猴, 马, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (AA 125-142), (Intracellular) antibodyP2RY12 适用: 人 WB, IP, FACS, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12) (AA 270-282), (Extracellular) antibodyP2RY12 适用: 人 WB, FACS, LCI, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Negative Control: (ABIN7582047)
Blocking Peptide:
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 15 μL or 50 μL double distilled water (DDW), depending on the sample size.
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浓度
- 1 mg/mL
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缓冲液
- Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1 % BSA, 0.05 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))
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别名
- P2RY12
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背景
- P2Y purinoceptor 12, P2RY12, ADP-glucose receptor, Platelet ADP receptor, HORK3,The P2Y receptors belong to the G-protein coupled receptor superfamily. They mediate the actions of the extracellular nucleotides (ATP, ADP, UTP and UDPA). Eight functional mammalian P2Y receptors have been described: P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13, and the UDP-glucose receptor, now renamed P2Y141-3. The P2Y12 receptor is co-expressed with the P2Y1 receptor on platelets leading to shape change, aggregation, and rise in intracellular Ca2+ upon activation. The only other expression of P2Y12 was found in brain, according to results of reverse transcription-polymerase chain reaction and northern blotting4. The P2Y12 receptor has become a target for potential therapeutic drugs for the treatment of thromboembolism and other clotting disorders4.
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基因ID
- 64805
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UniProt
- Q9H244
抗原
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