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Partner of Y14 and Mago (PYM1) 抗体

PYM1 适用: 小鼠, 大鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7074992
发货至: 中国
  • 抗原
    Partner of Y14 and Mago (PYM1)
    适用
    小鼠, 大鼠
    宿主
    克隆类型
    多克隆
    应用范围
    Immunofluorescence (IF), Immunohistochemistry (IHC)
    交叉反应
    大鼠
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein corresponding to Mouse PYM
  • 应用备注
    IHC/IF (M,R) 1:3000-1:6000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    Partner of Y14 and Mago (PYM1)
    别名
    PYM
    背景
    Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as an EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated.
    基因ID
    78428
    NCBI登录号
    NP_001164340
    UniProt
    Q8CHP5
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