MAP3K12 抗体
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北京 101111
Quick Overview for MAP3K12 抗体 (ABIN7074679)
抗原
See all MAP3K12 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse MAP3K12
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应用备注
- IHC/IF (H) 1:200-1:400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))
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别名
- MAP3K12
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背景
- This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.
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基因ID
- 26404
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UniProt
- Q60700
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途径
- MAPK Pathway
抗原
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