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- 抗原 See all MIIP 抗体
- MIIP (Migration and Invasion Inhibitory Protein (MIIP))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MIIP antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein corresponding to Mouse MIIP
- Top Product
- Discover our top product MIIP Primary Antibody
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anti-Migration and Invasion Inhibitory Protein (MIIP) (AA 251-350) antibody
MIIP 适用: 人, 大鼠 WB, IF (p), IF (cc), ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Migration and Invasion Inhibitory Protein (MIIP) antibodyMIIP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Migration and Invasion Inhibitory Protein (MIIP) (AA 1-388) antibodyMIIP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- IHC/IF (H) 1:600-1:1200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- MIIP (Migration and Invasion Inhibitory Protein (MIIP))
- 别名
- MIIP (MIIP 产品)
- 别名
- IIP45 antibody, AA553001 antibody, AI853621 antibody, D4Wsu114e antibody, Iip45 antibody, migration and invasion inhibitory protein antibody, MIIP antibody, Miip antibody
- 背景
- MIIP has 3 SEG (segments of low compositional complexity) domains, an RGD motif, and several potential phosphorylation sites. The C-terminal region of IGFBP2 interacts with a central 44-amino acid sequence of MIIP. MIIP inhibits glioma cells invasion and down-regulates adhesion- and motility-associated genes such as NFKB2 and ICAM1. It exhibits opposing effects to IGFBP2 on cell invasion. There are 2 named isoforms due to alternative splicing. Isoform 1 is expressed in brain but underexpressed in glioma tissues, at protein level. Isoform 2 is not detected in normal organs, but is expressed in gliomas with increasing levels with glioma progression.
- 基因ID
- 28010
- NCBI登录号
- NP_001020536
- UniProt
- A2A7Y5
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