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- 抗原 See all KIAA1524 抗体
- KIAA1524
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KIAA1524 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人, 大鼠
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein corresponding to Mouse CIP2A
- Top Product
- Discover our top product KIAA1524 Primary Antibody
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anti-KIAA1524 (KIAA1524) (AA 601-700) antibody
KIAA1524 适用: 人 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-KIAA1524 (KIAA1524) antibodyKIAA1524 适用: 人 IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-KIAA1524 (KIAA1524) (AA 230-560) antibodyKIAA1524 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-KIAA1524 (KIAA1524) (AA 269-301) antibodyKIAA1524 适用: 小鼠 WB 宿主: 兔 Polyclonal RB56267 unconjugated
anti-KIAA1524 (KIAA1524) (AA 537-567) antibodyKIAA1524 适用: 人 WB 宿主: 兔 Polyclonal RB57595 unconjugated
anti-KIAA1524 (KIAA1524) antibodyKIAA1524 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-KIAA1524 (KIAA1524) antibodyKIAA1524 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-KIAA1524 (KIAA1524) (AA 681-905) antibodyKIAA1524 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB (H,M,R) 1:500-1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- KIAA1524
- 别名
- CIP2A (KIAA1524 产品)
- 别名
- CIP2A antibody, p90 antibody, AA408511 antibody, AU018569 antibody, Cip2a antibody, Kiaa1524 antibody, KIAA1524 antibody, LOC100222895 antibody, RGD1310335 antibody, cell proliferation regulating inhibitor of protein phosphatase 2A antibody, RIKEN cDNA C330027C09 gene antibody, KIAA1524 antibody, cell proliferation regulating inhibitor of protein phosphatase 2A L homeolog antibody, CONSTANS interacting protein 2a antibody, CIP2A antibody, C330027C09Rik antibody, KIAA1524 antibody, cip2a.L antibody, CIP2a antibody, cip2a antibody, Cip2a antibody
- 背景
- Inhibition of protein phosphatase 2A (PP2A) activity has been identified as a prerequisite for the transformation of human cells. The protein, designated Cancerous Inhibitor of PP2A (CIP2A), interacts directly with the oncogenic transcription factor c-Myc, inhibits PP2A activity toward c-Myc serine 62 (S62), and thereby prevents c-Myc proteolytic degradation. In addition to its function in c-Myc stabilization, CIP2A promotes anchorage-independent cell growth and in vivo tumor formation. The oncogenic activity of CIP2A is demonstrated by transformation of human cells by overexpression of CIP2A. Importantly, CIP2A is overexpressed in two common human malignancies, head and neck squamous cell carcinoma (HNSCC) and colon cancer.
- 分子量
- 102 kDa
- 基因ID
- 224171
- NCBI登录号
- NP_766204
- UniProt
- Q8BWY9
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