Neuregulin 2 抗体 (Extracellular)
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- 抗原 See all Neuregulin 2 (NRG2) 抗体
- Neuregulin 2 (NRG2)
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抗原表位
- AA 297-311, Extracellular
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Neuregulin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- A Rabbit Polyclonal Antibody to Neuregulin-2
- 特异性
- Extracellular, N-terminus
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Mouse,human - identical
- 产品特性
- Anti-NRG2 (extracellular) Antibody (ABIN7043355, ABIN7044720 and ABIN7044721) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize Neuregulin-2 from rat, mouse, and human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)RDIRIKYGNGRKNSR, corresponding to amino acid residues 297-311 of rat Neuregulin-2
- 亚型
- IgG
- Top Product
- Discover our top product NRG2 Primary Antibody
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anti-Neuregulin 2 (NRG2) antibody
NRG2 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (AA 116-215) antibodyNRG2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D2 unconjugated
anti-Neuregulin 2 (NRG2) (AA 112-405) antibodyNRG2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) antibodyNRG2 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (Internal Region) antibodyNRG2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (AA 358-389), (C-Term) antibodyNRG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1278 unconjugated
anti-Neuregulin 2 (NRG2) (AA 116-215) antibodyNRG2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (AA 101-211) antibodyNRG2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (AA 618-836) antibodyNRG2 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (AA 830-855) antibodyNRG2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300
Application Dilutions Western blot wb: 1:200
- 说明
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Negative Control: (ABIN7236030)
Blocking Peptide: (ABIN7236030)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- Neuregulin 2 (NRG2)
- 别名
- NRG2 (NRG2 产品)
- 背景
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Neuregulin-2, Pro-neuregulin-2 membrane-bound isoform, Pro-NRG2, Neural- and thymus-derived activator for ErbB kinases, NTAK,Neuregulins (NRGs) are a multi member protein family involved in cell to cell communication. This family includes four human neuregulin paralogs NRG1-NRG4 which produce multiple isoforms through alternative splicing.NRGs are involved in several physiological processes including heart and peripheral nervous system development. They act in part by binding to the extracellular region of ErbB/HER transmembrane tyrosine kinases, leading to receptor dimerization and ultimately to the activation of a complex network of downstream signaling events1,2.NRG2 transcript levels markedly increase following birth, suggesting that NRG2 has important functions in the postnatal and adult brain. Several studies have also shown that NRG2 modulates glutamatergic transmission in GABAergic neurons and selectively affects GluN2B-containing NMDA receptors2,3.The region containing the NRG2 locus is associated with schizophrenia and other psychiatric disorders and genetically linked to ADHD in genome-wide scans2.
Alternative names: NRG2, Neuregulin-2, Pro-neuregulin-2 membrane-bound isoform, Pro-NRG2, Neural- and thymus-derived activator for ErbB kinases, NTAK - 基因ID
- 432361
- NCBI登录号
- NM_013982
- UniProt
- O35569
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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