Ephrin A1 抗体 (Extracellular)
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- 抗原 See all Ephrin A1 (EFNA1) 抗体
- Ephrin A1 (EFNA1)
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抗原表位
- AA 150-164, Extracellular
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Ephrin A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunochromatography (IC), Live Cell Imaging (LCI)
- 原理
- A Rabbit Polyclonal Antibody to Ephrin-A1
- 特异性
- Extracellular
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Mouse,rat - 13,15 amino acid residues identical
- 产品特性
- Anti-Ephrin-A1 (extracellular) Antibody is directed against an extracellular epitope of human Ephrin-A1. Anti-Ephrin-A1 (extracellular) Antibody (ABIN7043128, ABIN7044255 and ABIN7044256) can be used in western blot and live cell imaging applications. The antibody recognizes an extracellular epitope and thus is ideal for detecting Ephrin-A1 in living cells. It has been designed to recognize Ephrin-A1 from human, rat and mouse samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KITHSPQAHDNPQEK, corresponding to amino acid residues 150-164 of human Ephrin-A1
- 亚型
- IgG
- Top Product
- Discover our top product EFNA1 Primary Antibody
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anti-Ephrin A1 (EFNA1) antibody
EFNA1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) (Internal Region) antibodyEFNA1 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) (AA 19-182) antibodyEFNA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) antibodyEFNA1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Ephrin A1 (EFNA1) (AA 19-182) antibodyEFNA1 适用: 人 ELISA, WB, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) (AA 19-182) antibodyEFNA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) antibodyEFNA1 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) (Internal Region) antibodyEFNA1 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) (AA 101-205) antibodyEFNA1 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) (AA 1-205) antibodyEFNA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200-1:400
- 说明
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Negative Control: (ABIN7235302)
Blocking Peptide: (ABIN7235302)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- Ephrin A1 (EFNA1)
- 别名
- EFNA1 (EFNA1 产品)
- 背景
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EPH-related receptor tyrosine kinase ligand 1, LERK1, EFNA1,Ephrin-A1, a ligand of type-A Eph receptor tyrosine kinases and the Eph/ephrin system, has been shown to play important roles in the nervous system, tissue patterning and cell adhesion through receptor-ligand interactions and intracellular signaling1. Ephrins can be divided into two subclasses: ephrin A and ephrin B. Ephrin A ligands (ephrin A1-A5) are anchored to the cell surface via a glycosylphosphatidylinositol (GPI) anchor and bind to Eph A receptors (Eph A1-A8), whereas ephrin B ligands (ephrin B1-B3) have transmembrane and cytoplasmic domains and interact with Eph B receptors (Eph B1-B6)2.Eph receptors and ephrins are highly expressed in the brain and in the developing nervous system, where they have well-known roles in the establishment of neuronal connectivity by guiding axons to the appropriate targets and regulating the formation of synaptic connections. Ephrins are expressed in numerous regions of the vertebrate embryo including the ectoderm, mesoderm, and endoderm3.Ephrin (Eph) receptors are frequently overexpressed in a variety of human malignant tumors, and are associated with tumor growth, invasion, metastasis and angiogenesis. Recent studies using clinical samples showed that ephrin-A1 expression was up-regulated in colorectal cancer and hepatocellular carcinoma and positively correlated with a poor prognostic value4.
Alternative names: Ephrin-A1, EPH-related receptor tyrosine kinase ligand 1, LERK1, EFNA1 - 基因ID
- 1942
- NCBI登录号
- NM_004428
- UniProt
- P20827
- 途径
- RTK signaling
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