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CTCF 抗体 (AA 451-550)

Name: CTCF 抗体 (AA 451-550)
SKU: ABIN703976
Availability: OutOfStock

This anti-CTCF antibody (ABIN703976) is a Rabbit Polyclonal antibody detecting CTCF in ELISA, IHC (p), IF (cc), IF (p), IHC (fro). Suitable for Human.

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-CTCF Polyclonal Antibody, Unconjugated (ABIN703976) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (CTCF 抗体 (AA 451-550))

IHC

Formalin-fixed and paraffin embedded human rectal carcinoma labeled with Anti-CTCF Polyclonal Antibody, Unconjugated (ABIN703976) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (CTCF 抗体 (AA 451-550))

IHC

2 images

产品编号 ABIN703976

发货至: 中国

Datasheet as PDF

Quick Overview for CTCF 抗体 (AA 451-550) (ABIN703976)

抗原

See all CTCF 抗体

CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

适用

人

宿主

兔

克隆类型

多克隆

标记

This CTCF antibody is un-conjugated

应用范围

ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product CTCF Primary Antibody

抗原表位
5

4

4

2

2

2

1

1

1

1

1

1

1

1
AA 451-550

交叉反应

人

预测反应

Mouse,Rat,Dog,Cow,Pig,Horse

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human CTCF

亚型

IgG
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (AA 1-260) antibody
CTCF 适用: 人 WB, IHC, IF, IP, ChIP 宿主: 兔 Polyclonal unconjugated

anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) antibody
CTCF 适用: 人 WB, ChIP-seq, CUT&RUN 宿主: 兔 Monoclonal unconjugated Recombinant Antibody

anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) antibody
CTCF 适用: 人 WB, IF, IP, ChIP 宿主: 兔 Monoclonal unconjugated

anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (C-Term) antibody
CTCF 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (AA 1-260) antibody
CTCF 适用: 人 WB, IHC, ELISA, ChIP 宿主: 兔 Polyclonal unconjugated

anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (AA 334-364) antibody
CTCF 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB53773 unconjugated

anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (N-Term) antibody
CTCF 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 猴, 豚鼠, Bat, 小鸡, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (AA 521-727) antibody
CTCF 适用: 人, 小鼠, 大鼠 WB, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (AA 1-100) antibody
CTCF 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) antibody
CTCF 适用: 人 ICC, DB 宿主: 小鼠 Monoclonal 252C3a unconjugated

应用备注

ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

别名

CTCF

背景

Synonyms: MRD21, Transcriptional repressor CTCF, 11-zinc finger protein, CCCTC-binding factor, CTCFL paralog, CTCF
Background: Chromatin binding factor that binds to DNA sequence specific sites. Involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. Acts as transcriptional repressor binding to promoters of vertebrate MYC gene and BAG1 gene. Also binds to the PLK and PIM1 promoters. Acts as a transcriptional activator of APP. Regulates APOA1/C3/A4/A5 gene cluster and controls MHC class II gene expression. Plays an essential role in oocyte and preimplantation embryo development by activating or repressing transcription. Seems to act as tumor suppressor. Plays a critical role in the epigenetic regulation. Participates in the allele-specific gene expression at the imprinted IGF2/H19 gene locus. On the maternal allele, binding within the H19 imprinting control region (ICR) mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to IGF2. Plays a critical role in gene silencing over considerable distances in the genome. Preferentially interacts with unmethylated DNA, preventing spreading of CpG methylation and maintaining methylation-free zones. Inversely, binding to target sites is prevented by CpG methylation. Plays a important role in chromatin remodeling. Can dimerize when it is bound to different DNA sequences, mediating long-range chromatin looping. Mediates interchromosomal association between IGF2/H19 and WSB1/NF1 and may direct distant DNA segments to a common transcription factory. Causes local loss of histone acetylation and gain of histone methylation in the beta-globin locus, without affecting transcription. When bound to chromatin, it provides an anchor point for nucleosomes positioning. Seems to be essential for homologous X-chromosome pairing. May participate with Tsix in establishing a regulatable epigenetic switch for X chromosome inactivation.

基因ID

10664

UniProt

P49711