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IGF1R 抗体 (pTyr1161)

This anti-IGF1R antibody is a 兔 多克隆 antibody detecting IGF1R in WB, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7265182
发货至: 中国

Quick Overview for IGF1R 抗体 (pTyr1161) (ABIN7265182)

抗原

See all IGF1R 抗体
IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This IGF1R antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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    pTyr1161

    产品特性

    Phosphorylated antibody

    纯化方法

    Affinity purification

    免疫原

    A phospho specific peptide corresponding to residues surrounding Y1161 of human IGF1R

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000 IHC 1:50-1:100 IF 1:100-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

    别名

    IGF1R

    背景

    This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    分子量

    Observed_MW: 95 kDa

    Calculated_MW: 154 kDa

    基因ID

    3480

    UniProt

    P08069

    途径

    RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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